2025 Annual Report
Letter from the Executive Director
Rapid shifts in funding, policy, and need created a landscape marked by uncertainty and almost constant change — requiring clarity, adaptability, and resolve from organizations that effectively work to improve care and outcomes. At Ariadne Labs, we navigated this moment with a clear focus on what matters most: advancing practical solutions that make health care safer, more equitable, and more effective.
As I reflect on 2025, I see not just challenges, but deeply meaningful progress and reasons for optimism. While unprecedented fiscal and political pressures across public health continue, we have responded with urgency and determination to sustain and strengthen our work. Even before major research funding cuts occurred, in the first week of February 2025, we launched an intensive funding and work alignment proposal sprint, resulting in the submission of more than 70 new proposals — nearly 20 of which have already been funded — enabling us to move our work forward in novel and impactful ways while maintaining our core mission.
Alongside our focused push to secure vital funding in a challenging climate, we continued to design, test, and spread solutions aimed at saving lives and reducing suffering worldwide. In 2025, our work reached more than 148 million patients, and we partnered directly with more than 58,000 health care professionals across the globe. Our BetterBirth program published landmark findings that showed the WHO Safe Childbirth Checklist reduces stillbirths by 11%, reinforcing its potential to save newborn lives at scale. We launched new collaborations to expand access to rural healthcare through mobile delivery models and to establish the first multi-state genomic newborn sequencing initiative. We also initiated new work to examine how artificial intelligence can strengthen health care delivery across the globe and resumed critical projects paused by prior funding cuts, including testing a cesarean section checklist with the potential to save tens of thousands of lives globally and launching a coalition to build a scalable pathway for early detection of type 1 diabetes risk.
We also marked an important organizational milestone with our move in December 2025 from 401 Park Drive in Boston to Assembly Row in Somerville, Massachusetts. Our new space offers expanded opportunities for collaboration, connection, and community-building, supporting how we work today and positioning us for the future.
Now more than ever, we are deeply grateful to our community for your steadfast support. Your partnership makes it possible for us to advance our mission and remain committed to saving lives and reducing suffering for every person, everywhere.
Looking ahead, we know the future of public health will continue to evolve in complex and unexpected ways. While change brings challenge, it also creates opportunity to think differently, to adapt quickly, and to build stronger solutions. We approach 2026 with renewed optimism, momentum, and deep appreciation for the community that stands with us as we move into the next chapter of our work.
Asaf Bitton
Executive Director
Past Annual Reports
